So this new data comes with a big caveat. than it is in South Africa?ĭOUCLEFF: Yeah. But you said in this population - is there reason to believe the vaccine effectiveness will be different here in the U.S. Also, this protection seems to hold up in people with some risk factors, such as diabetes, as well as in older people. So that's a drop from 90%, but it does indicate that the vaccine is still working really well to keep people out of the hospital. So the researchers found that two shots of the Pfizer vaccine still offered about 70% protection against severe disease in this population. In this study, protection against severe disease dropped a bit, but not as much. MARTIN: Then what about for severe disease? How well does the vaccine protect against that?ĭOUCLEFF: Yeah. And just to emphasize here, this is for protection against infection. So at 30%, they're going to be many, many breakthrough infections. during the delta surge, the mRNA vaccines had an effectiveness of about 60 to 70%. That's pretty low, right?ĭOUCLEFF: It is quite low. MARTIN: Thirty percent doesn't sound very good, Michaeleen.
In this population, the vaccine's effectiveness against infection dropped to about 30% for omicron compared to about 80% against the previous variant. Nearly half of those people had received two doses of the Pfizer vaccine. And in the study, scientists analyzed data from about 78,000 people likely infected with omicron. Hey, Michaeleen.ĭOUCLEFF: So the findings come from South Africa's largest private health insurer, called Discovery Health, and the South African Medical Research Council. Here to tell us what they found, NPR's global health correspondent Michaeleen Doucleff. Scientists in South Africa are now releasing the first data looking at how well the vaccines will work against this variant.
It has an exceptionally high number of mutations in it, and it appears to be more transmissible than the delta variant.
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